Research
Modality Partnership participates in medical research projects vital in helping to extend the frontiers of medical science and knowledge. Most of the projects we work on are connected to therapeutic interventions.
We are therefore pleased to give suitable patients the opportunity to participate in relevant studies many of which involve diagnostic tests and treatments which would not otherwise be routinely available.
Studies currently available for participation are listed below (note, they maybe only available in certain divisions).
Current studies
CLASP 5 – Cancer: Life affirming survivorship support in primary care
CCP – Co-ordinated Programme to Prevent Arthritis: Can We Identify Arthritis at a Pre-Clinical Stage
Barack d – Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease
Decide – effectiveness of a dapagliflozin compared to Standard of Care
COPD – a post-authorization Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events inCOPD Patients Using Inhaled UMEC/VI Combination or Inhaled UMEC versus Tiotropium
Completed studies
We would like to thank all our patients who have taken part in the studies mentioned below. Without your help we would not be able to advance our knowledge on these medical problems.
Af gen UK -Long-term Registry of Patients with Atrial Fibrillation UK Extension (AF-GEN-UK) Study
CONDUCT – COllectioN Devices to reduce Urine ConTamination
HOME BP – Home & Online Management and Evaluation of Blood Pressure
ARRISA – At-Risk Registers Integrated into primary care to Stop Asthma crises in the UK
PACT – Personalised medicine for Asthma ConTro
PLUS -pic site -A Phase 4, Double-Blind, Randomized, Placebo-controlled, Multi-Center Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Men with Overactive Bladder (OAB) Symptoms While Taking the Alpha Blocker Tamsulosin Hydrochloride for Lower Urinary Tract Symptoms (LUTS) due to Benign Prostatic Hyperplasia (BPH).
INVICTUS – A phase IIb study to determine the safety and efficacy of candidate influenza Vaccine MVA-NP+M1 in combination with licensed Inactivated influenza vaccine in adults aged 65 years and above
OPTIMISE – Optimising Treatment for Mild Systolic hypertension in the Elderly: a randomised controlled trial.
PROLIA – Osteoporosis Diagnosis and treatment in Community-dwelling Women ≥70 Years of Age Managed in Primary Care Setting in Europe. Across-Sectional Observational Study
ALICE: Antivirals for influenza Like Illness? An rCt of Clinical and Cost effectiveness in primary Care
CREDENCE – (Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation). The objective of the study is to examine whether canagliflozin can slow the progression of diabetic nephropathy, a form of renal impairment that is the most common cause of end-stage renal disease worldwide.
CANDID – This trial looked for patients to help doctors to develop guidelines in the future for patients who currently have bowel or lung symptoms who may then later on develop either bowel or lung cancer respectively.
ARCHIE (The early use of Antibiotics for at Risk Children with Influenza in primary care)
TASMINH4 (Telemonitoring and/or self-monitoring of blood pressure in hypertension) – Our research aims to find out whether high blood pressure is better controlled using blood pressure readings taken by patients at home compared to clinic readings.
TOAST(Treatment Options without Antibiotics for Sore Throat)–Do oral corticosteroids provide clinical and cost effective symptom relief for sore throat?
OSAC (Oral Steroids for Acute Cough) – a study aiming to find out whether giving people a 5 day course of steroid tablets can help treat their chest infection.
DARE (Diabetes Alliance for Research in England)–This study is aiming to improve our understanding of diabetes and its complications by understanding the role of environmental and genetic influences in diabetes and its associated complications.
YDX (Young Diabetes in Oxford) – Looking at the characteristics of people diagnosed with diabetes aged 45 years or younger.
HEAT(Helicobacter Eradication Aspirin Trial) – a study looking at whether treating a type of stomach infection called ‘Helicobacter’ in people who take aspirin might reduce their risk of developing stomach ulcers.
Clinical Practice Research Datalink
The practice is working with the Medicines & Healthcare products regulatory agency & National Institute for health research contributing anonymised data for the Clinical Practice Research datalink (CPRD).
CPRD data is used for approved medical and public health research including:
- Investigating side effects of medicines
- Investigating causes of disease and medical disorders and associated risk factors
- Looking into the outcomes of treatments
- Examining areas of unmet medical need
- Identifying ways of improving screening or diagnosis
- Evaluating which services or treatments work best
RCGP Research and Surveillance centre
The practice is working with the RCGP research and surveillance centre contributing pseudonymised data for national research and surveillance. These data enable continuous monitoring of infections and diseases in the community and is used in ethically approved research.
IQVIA Medical Research Extraction Scheme
The practice is working with the IQVIA Medical Research Extraction Scheme contributing pseudonymised data for medical and public health research.
